Amodiaquine-induced Agranulocytosis: Toxic Effect of Amodiaquine in Bone Marrow Cultures In Vitro
Identifieur interne : 003B02 ( Main/Exploration ); précédent : 003B01; suivant : 003B03Amodiaquine-induced Agranulocytosis: Toxic Effect of Amodiaquine in Bone Marrow Cultures In Vitro
Auteurs : D. E. Lind ; J. A. Levi ; P. C. VincentSource :
- British Medical Journal [ 0007-1447 ] ; 1973-02-24.
English descriptors
- Teeft :
- Agranulocytosis, American journal, Amodiaquine, Bone marrow, Bone marrow biopsy, Bone marrow cells, Bone marrow cultures, Case report, Colony formation, Feeder layers, Lower concentrations, Lung fields, Lymph node, Marrow, Nodular opacities, Normal control, Normal limits, Other patients, Platelet, Respiratory symptoms, Same time, Toxic effect, Transplantation, Transplantation proceedings, Triplicate cultures.
Abstract
A case of agranulocytosis is reported in which amodiaquine, to which the patient had been exposed, was found to be toxic to the patient's bone marrow cells when these were cultured in an agar colony system in vitro. This technique should be investigated in other patients with agranulocytosis as a possible means of detecting toxic agents.
Url:
DOI: 10.1136/bmj.1.5851.458
Affiliations:
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Le document en format XML
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